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Metabolic Studies in Obese Zucker Murine Models An early preclinical study evaluated the metabolic implications of AOD-9604 in obese Zucker rats, a validated rodent model of obesity characterized by leptin receptor deficiency and hyperphagia

Avoid injecting into the same spot repeatedly

Metabolic signaling and longevity-related research

MOTS-c has a circulating half-life of approximately 2 to 4 hours

Following OA induction, the rabbits were randomly divided into four groups with 8 subjects, each receiving a different weekly intra-articular treatment starting four weeks after the first collagenase injection