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Los ensayos humanos son escasos y de baja calidad metodolgica (principalmente estudios pequeos no controlados de los aos 90 en enfermedad inflamatoria intestinal)

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IL-1 regulates expression of Cx32, occludin, and claudin-2 of rat hepatocytes via distinct signal transduction pathways

Regulatory Considerations TB500 is not approved for human use by regulatory agencies in many countries, presenting legal and quality control challenges