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The Therapeutic Goods Administration (TGA), which regulates clinical trials in Australia, requires that the sponsor of a clinical trial must be an Australian entity or have a local representative if the sponsor is based overseas

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Furthermore, chronic systemic inflammation induces a state of anabolic resistance within the muscle tissue

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and plasma and erythrocyte analysis of cobalamin coenzymes, which can reveal deficiencies of methylcobalamin or adenosylcobalamin