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It achieve tolerance to anticancer drugs through mechanisms such as epigenetic modifications, transcriptional regulation, and metabolic reprogramming

The JAK2/STAT3 and ERK pathways were involved in the possible molecular mechanism
10.1016/j.taap.2009.01.019 41

Our findings indicate that the combination of (-)-Vestitol and Salviolone significantly modulates this pathway, likely through a multifaceted effect on various neurotransmitter systems
However, the increase in thigh girth was not significantly different between study conditions
H., Inhalable mRNA Nanoparticle With Enhanced Nebulization Stability and Pulmonary Microenvironment Infiltration, ACS Nano 18 (2024): 2420424218
