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It is considered one of the most common diseases that lead to mortality and morbidity worldwide

The liver produces it and distributes it to every cell, which promotes cellular defence against oxidative stress, detoxifies, and boosts immunity
Tumorassociated macrophages secrete CCchemokine ligand 2 and induce tamoxifen resistance by activating PI3K/Akt/mTOR in breast cancer

This extensive research timeline provides substantial evidence regarding both short-term efficacy and longer-term safety considerations, though ongoing studies continue to expand our understanding of this medication's full clinical profile
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Yoon et al., 2006
