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3D cell culture models Most in vitro studies of ECD rely on 2D cell models where a monolayer of ECs is grown on tissue culture polystyrene (TCPs) plates [237]

Bonferronis correction was applied to analyses correlating BAL fluid or intracellular GSH, GSSG, and GSH:GSSG to up to 5 gene expression variables or clinical parameters to adjust for multiple comparisons

Electron leakage from complex I and complex III will react with oxygen and form ROS, including hydrogen peroxide, hydroxyl radicals, and other reactive oxygen and nitrogen species [10,11]

Current literature emphasizes mechanistic exploration rather than definitive biological outcomes

Metabolism as a new avenue for hepatocellular carcinoma therapy

Appropriate supplementation or an IV administered by a doctor remains the best way to boost glutathione levels