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PMID: 27713245

Unpredictable Allergic Reactions and Hives (MCAS): Oxidative stress acts as a direct trigger for mast cell degranulation

Specifically, it reduced the expression of iNOS, COX-2, TNF-, IL-1 and NF-B p65 in transgenic mice that overexpress tau gene that has P301S mutation that leads to frontotemporal dementia in men

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However, its equally important to be aware of potential side effects

The effect of postinjury administration of polyethylene glycol-conjugated superoxide dismutase (Pegorgotein, Dismutec) or lidocaine on behavioural function following fluid-percussion brain injury in rats