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Meanwhile, the release of BSO was able to effectively inhibit the de novo synthesis of GSH, which inactivated GPX4 and further promoted LPO accumulation by blocking the conversion of LPO to lipid alcohols

Isolated sulfite oxidase deficiency

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have also reported that vitamin C and E supplementation reduced protein carbonyl formation during exercise-induced and alcohol-induced oxidative stress, respectively [40-41]

Ferrostatin-1, when applied as an eye drop, increased corneal epithelial survival by 60%, and the levels of Fe 2+ and MDA decreased in hyperosmolar models

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