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The absorption of B12 is a complicated process but the two main components that are needed are the Hydrochloric acid in your stomach, which releases the B12 from food, and a protein called Intrinsic Factor which is produced in the lining of your stomach and which enables the absorption of B12 in the Ileum

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L., Song, Y., Vidal-Alaball, J., & Liu, T

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Intramuscular B12 injections bypass the digestive system for faster, more complete absorption than oral supplements, making them highly effective in treating deficiency and preventing complications like anemia, weakness, and neurological symptoms

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