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Microglia undergo metabolic reinvention: early succinate accumulation drives inflammatory rage, yet later oxidation of this metabolite switches them to anti-inflammatory phagocytes [37]
3.1.2 Chemotherapy induces acute BM injury by causing HPC apoptosis According to some studies, acute BM injury occurs soon after chemotherapy due to inducing apoptosis of hematopoietic cell [55, 56]
Mol Psychiatry 2022:1 [DOI] [PMC free article] [PubMed] [Google Scholar] 136.Tsai SY, Chen HJ, Chen C, Lio CF, Kuo CF, Leong KH, Wang YT, Yang TY, You CH, Wang WS (2019) Increased risk of chronic fatigue syndrome following psoriasis: a nationwide population-based cohort study
Quellen Peter Billigmann und Stefan Siebrecht (2004): Physiologie des L-Carnitins und seine Bedeutung fr Sportler
Based on previous data coming from preclinical and clinical studies and its excellent clinical safety profile, ALCAR is a promising treatment for ALS
