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doi: 10.1016/j.bbacli.2015.08.004 28 LongYWangYCYuanDZDaiXHLiaoLCZhangXQet al

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Administration Timing and Duration Published studies show variation in treatment duration based on the tissue and injury model: Acute injury models: Treatment typically begins immediately (within 24 hours) and continues for 2-4 weeks Chronic condition models: Treatment periods extend to 4-8 weeks, with some investigations running 12 weeks to assess long-term remodelling Preventative models: Some studies administer BPC-157 before injury induction, showing protective effects even when dosing occurs 24 hours prior to damage The peptides half-life has not been extensively characterised in published pharmacokinetic studies, but dosing intervals of 12-24 hours appear standard across most protocols, suggesting sufficient duration of action to avoid multiple daily administrations in many research contexts

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(7) Chronic inflammation is closely linked to oxidative stress and plays a significant role in the progression of these diseases, worsening symptoms and contributing to ongoing tissue damage