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Another drawback to these tests is that other factors, such as inflammation, can cause these biomarkers to be abnormally high

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doi: 10.1038/srep16429

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Mutations in AML are associated with aberrant histone acetylation, whose mutations can alter lysine demethylase (KDM) activity and enhance histone deacetylation, leading to the accumulation of 2-HG

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