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SKN-1 promotes cold stress resistance After determining a requirement for neuronal signaling in cold-shock-induced lipid reallocation, we next wondered what intermediate factors were needed to translate the cold stimulus into a signal to mobilize resources

Nrf2, a CapnCollar transcription factor, regulates induction of the heme oxygenase-1 gene

This chemical flexibility renders it one of the most powerful natural free-radical scavengers known to human biology

Since cortisol is hydrophobic, it can interact with the sequestered tails of the phospholipids in the center of the plasma membrane

The R radicals reaction with O 2 yielding ROO