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This suggested that SF was exerting a pharmacodynamic action that reflected induction of GSTs by SF, thereby shunting the reactive epoxide intermediate away from nucleophiles in DNA, where it would have mutagenic and carcinogenic effects, and toward GSH, which allowed it to be further metabolized and excreted in the urine

[10] Zostavax (Merck), in use since 2006, [11] is an attenuated vaccine which consists of a larger-than-normal dose of varicella vaccine

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They are in different categories, from pharmacogenomics to surrogate markers of neurotoxicity

Lack of the second enzyme in the transsulfuration pathway, cystathionine -lyase, results in accumulation of cystathionine in tissues and the loss of cystathionine in the urine, but no apparent disorder

Originating from ectoderm-derived neural stem cells in the neural tube, astrocyte lineage commitment begins with radial glia cells, which express classical markers such as GFAP, glutamate aspartate transporter (GLAST) and calcium-binding protein (S100B) 1