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Consistent with this general mechanism, oxidative stress is a major proposed pathogenic mechanism for neurodegenerative disorders in which mitochondrial defects have been reported, including Parkinsons, Huntingtons, and Alzheimers diseases

It was also demonstrated that the exposure of lung epithelial cells A549 and L132 to gliotoxin for 24 h resulted in a significant increase in the proportion of cells in S-phase (3039%), with a concomitant decrease in G2/M-phase

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20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo

Results Silencing of SlBEL11 affects carotenoid accumulation in tomato fruit The SlBEL11 belongs to the BEL1-like Homeodomain (BEL1-like) TFs family with high expression abundance in the red stage and involved in the regulation of chlorophyll synthesis and fruit pigmentation in tomato fruit ( SlBEL11 RNAi tomato fruits accumulate more chlorophyll at mature green stage, we also found that it still remained yellow at the red stage (Figure 1D)

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