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Rather than targeting a single receptor or pathway, this advanced peptide combination activates multiple interconnected signaling networks while simultaneously suppressing inflammatory cascades that can impair healing, creating a comprehensive regenerative environment beyond what individual components might achieve alone

Acknowledgments The authors would like to thank Xu ZH from the Department of Endocrinology, Wuhan Central Hospital, Wuhan, Hubei Province, China for assisting with paper editing and data discussion

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