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Further mechanistic studies have shown that bortezomib effectively increases the level of NCOA4 by preventing proteasomal degradation, confirming its role in enhancing ferritinophagy

It has been observed that a notable number of MDSCs can effectively impair T cell responses in DLBCL (194)

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The resulting upregulation of NADPH can consequently mitigate ROS levels

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Duong C, Seow HJ, Bozinovski S (2010) Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice