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Some of these CD38-specific hcAbs have been shown to inhibit the GDPR cyclase activity of CD38, while others induce mechanisms of cytotoxicity in mouse tumor models [91]

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10.2147/ott.s259114 OncoTargets Ther

Karamitros, Nestl Health Science, United States Updates Copyright 2023 Swartz, Shieh, Gulasarian, Curtis, Hofmann, Baker, Templeton and Olson

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Catalase and GPx are functionally similar enzymes and they play a role in the detoxification of hydrogen peroxide and thus in the reduction of free radical oxidation level [6]