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Effects of acute alcohol on excitability in the CNS

Notably, the findings demonstrated that 5-Aza may be considered a valuable treatment option to improve OS in AML patients for whom intensive chemotherapy is not a viable strategy (OS 5-Aza group: 8.9 months

Instead, asparagine supplementation enhances the expression of glutamine synthetase (GLUL) and increases intracellular glutamine usage via glutaminolysis, resulting in the recovery of global protein translation that is blocked by glutamine deprivation 45

Kinetic measurements were performed under these conditions by measuring the increase of the colored reaction products photometrically (Fig