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At 3 months, a statistically significant higher concentration of sperm was noted in the study group (40.51 18.66 x 10 6 /ml), compared to the control (30.3 17.5 x 10 6 /ml) (p=0.001)

The present document focuses on a thorough review of the literature on worldwide cannabis use, the role of the endocannabinoid system in the pathophysiology of CHS, diagnostic criteria, and current management of CHS

Meanwhile, the bidirectional relationship between TMAO and bile acid metabolism also deserves further exploration, as they jointly regulate FXR signaling

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B-cell specific ablation of ChAT increases the mortality of mice subjected to partial hepatectomy compared to their wildtype counterpart, due to dysregulation of 7nAChR expressing Kupffer cells and CD8 + T cells, limiting their regenerative capacity and producing harmful IFN-, respectively (112)

Accumulating evidence indicates that OS not only triggers inflammatory responses but also directly contributes to liver damage in ALD (Louvet and Mathurin, 2015)