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Conclusions Our data implicate that exogenous antioxidants NAC and GSH, by reducing the intracellular ROS levels and inducing TMBIM expression, promoted HCC formation and tumor growth, and counteracted the therapeutic effect of Sorafenib

Non-Surgical Alternatives Oral Glutathione Supplementation: Highly useful for minor maintenance, but possesses notoriously low biological efficacy (only 15-20% absorption) due to severe gastric acid destruction

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Dzau V.J., Hodgkinson C.P

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In this model, cerebral injury correlated with an increase in oxidative stress markers and accelerated caspase 3 activation
