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However, under pathological conditions involving inflammation and oxidative bursts leading to the oxidation of internal Cys thiols, disulfide cross-links are generated between internal Cys domains rendering the mucus to be heavily crosslinked [37]
In case you suffer from kidney problems, heart disorders, or high blood pressure, make sure to contact your doctor
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The clinical effects of these disorders depends on the severity of enzyme deficiency and whether the -glutamyl cycle also is affected in non-erythroid tissues
Xu et al., 2013
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