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Tranexamic acid acts mainly via the plasminogen activator-plasmin system to prevent UV radiation-induced pigmentation in melasma

Patel S., Ashwanikumar N., Robinson E., et al., NaturallyOccurring Cholesterol Analogues in Lipid Nanoparticles Induce Polymorphic Shape and Enhance Intracellular Delivery of mRNA, Nature Communications 11, no

TPH: Tryptophan hydroxylase

Longer-term causes of zinc toxicity include occupational exposure to zinc [147] and iatrogenic causes such as overprescribing of zinc-containing medication, zinc present in dental fixtures (though modern preparations in the UK and US are now zinc-free) and overconsumption of over-the-counter zinc supplements [148]