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Ein Hauptsymptom niedriger Glutathion-Spiegel ist ein schwerwiegendes Energiedefizit

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[DOI] [PubMed] [Google Scholar] 158.Calabria D., Calabretta M.M., Zangheri M., Marchegiani E., Trozzi I., Guardigli M., Mirasoli M

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GSTM2 modulates growth of LDs via ASK1-p38/JNK signalling The growth of LDs is important in increasing the cellular capacity for lipid storage

The latter can interact with superoxide (O 2 ) to form peroxynitrite (OONO ) and hydroxyl radical (OH ) that triggers poly(ADP-ribose) polymerase 1 activation, which initiates apoptosis
