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The combination of ginkgetin and cisplatin (DDP) decreased the SLC7A11 and GPX4 expression as well as the GSH/GSSG ratio and increased labile iron pool and lipid peroxidation to mediate ferroptosis in EGFR wild-type non-small-cell lung cancer

Conversely, NF B activates genes particularly involved in the inflammatory response, as well as in modulating the cellular response to oxidative injury