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In preclinical studiesmeaning those done in labs and on animalsit has demonstrated a remarkable ability to promote healing

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O'Dwyer PJ, Hamilton TC, LaCreta FP, Gallo JM, Kilpatrick D, Halbherr T et al

Various structural alterations were made at the N-terminal such as substitution of D-norleucine for L-norleucine, N-acetylation of norleucine, and replacement of norleucine with GABA in order to improve overall stability by reducing susceptibility to aminopeptidases

The epidermal barrier function is dependent on the serine protease CAP1/Prss8