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These findings establish the mechanistic basis for the compound and provide proof of concept for its metabolic effects

Final Thoughts In the world of body optimization, peptides are the next frontier, not just for elite athletes or biohackers, but for anyone serious about improving their metabolic health and longevity

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Also, mice carrying a genetic mutation that lack one of the igf1r alleles ( igf1r +/ ) show a 10 % reduction in post-natal growth, insulin resistance and glucose intolerance [237]

By comparison, orlistat (Xenical) produced approximately 3-4 kg more weight loss than placebo over 12 weeks in its pivotal trials, and GLP-1 agonists produce 8-15 kg more than placebo

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