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Unlike compounds such as vitamin E or beta-carotene, AST readily crosses the bloodbrain barrier and acts across both hydrophilic and lipophilic environments, enabling broad neuroprotective effects

Panminerva Med 45(1):713 Halliwell B (2018) Artefacts with ascorbate and other redox-active compounds in cell culture: epigenetic modifications, and cell killing due to hydrogen peroxide generation in cell culture media
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In epilepsy patients, repeated seizures and prolonged medication can lead to reactive oxygen species production, causing neuronal damage

Phytomedicine 136 , 156285 (2025)
