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10.1016/j.archger.2022.104855 Arch
Leucine-rich-2-glycoprotein 1 (LRG1) is a novel pro-angiogenic factor that has demonstrated to promote angiogenesis by enhancing ALK-1signaling pathway in both diabetic ocular disease and DN mouse models (Wang et al., 2013
doi: 10.1021/acs.jafc.3c02429 40 XuguangHAofeiTTaoLLongyanZWeijianBJiaoG
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Notably, catalases specificity for hydrogen peroxide poses constraints in conditions where other reactive oxygen species contribute to oxidative stress, necessitating strategies for more comprehensive targeting approaches [183]

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