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The RNA methyltransferases encoded by the METTL3 and METTL14 genes incorporate methyl groups into adenine and cytidine residues in mRNA molecules utilizing SAM as the methyl donor

Arch Pathol Lab Med 139(7):876887 Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N et al (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntingtons disease