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The reason is physiological, not arbitrary

In combination with other vitamins it helps in strengthening the immune system, improves metabolism of the body and is essential for the nervous system

Oxidative Stress Promotes Polarization of Human T Cell Differentiation toward a T Helper 2 Phenotype

Appetite effects are not strongly characterized in either direction in the current evidence base
Stainless steel needles are commonly preferred for B12 injections

In pernicious anemia, the immune system thinks that the parietal cells or the intrinsic factor protein are foreign invaders, so it attacks and destroys them
