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Research demonstrates that GHK-Cu stimulation of collagen synthesis begins at concentrations between 10 and 10 M and maximizes at 10 M, with effects independent of changes in cell proliferation, indicating direct activation of synthetic machinery rather than simply increasing fibroblast numbers

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and, taking their submissions into consideration to revise the draft, followed by review by the Agencys Health, Medical and Research (HMR) Committee.
