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The most important consideration is consistency

J Appl Physiol (1985)

Proper Storage and Handling of B12 Injections Keeping B12 injections stored properly is key to their safety and effectiveness

Vitamin B 12 & Health

Absorption and Storage of Vitamin B12 Once administered, vitamin B12 is absorbed into the bloodstream and stored primarily in the liver

But usually, a series of treatments provide the most noticeable benefits
