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The process is facilitated by inhibition of cystine uptake by System Xc-, which reduces cellular GSH levels
The molecular nexus of this multilayered immunomodulation is the coordinated regulation of key intracellular signaling pathways by probiotics
It also upregulates autophagy, facilitating the clearance of protein aggregates from neurons
10.1371/journal.pone.0039953 PLoS ONE 15 BlandiniF.NappiG.GreenamyreJ
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Recently, antibodydrug conjugates (ADCs), which can directly deliver potent cytotoxic drugs to cancer cells with appropriate target antigens while avoiding toxic effects on healthy cells, have gained increasing attention
