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Tesofensine is a powerful weight loss compound that inhibits the reuptake of dopamine, serotonin, and norepinephrine, effectively reducing appetite and food cravings

doi:10.1007/s12035-014-8648-2 Sheridan PA, Beck MA

Of a consecutive sample of 3988 discharged patients, 1555 were excluded (796 declined to participate and 759 were unable to be contacted) and the remaining 2433 patients were enrolled

Self-reported community sources describe transient appetite shifts and occasional loose stool in the first 1-2 weeks of use

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While experimental findings point to diverse biological actions, mechanisms remain uncertain and outcomes appear context-dependent