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doi: 10.1002/cpt.1437 220 ShimazuS.HirashikiA.OkumuraT.YamadaT.OkamotoR.ShinodaN.et al (2013)

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Additionally, the results of four clinical trials or prospective cohort studies in 2008 and 2011 showed that LC supplementation was beneficial in patients with HE, including those with advanced cirrhosis complicated by HE, both in terms of blood ammonia levels, fatigue, depression, and neurological tests such as cognitive and mobility