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Do not shake the vial aggressively

PLoS ONE 11:e0154683 Han X, Yao W, Liu Z, Li H, Zhang Z-J, Hei Z, Xia Z (2016b) Lipoxin A4 preconditioning attenuates intestinal ischemia reperfusion injury through Keap1/Nrf2 pathway in a lipoxin A4 receptor independent manner

They made this hypothesis based on the autopsies of 21 diabetic patients
This is completely normal and part of the process

A 10mg vial becomes more economical at higher doses (1.0mg and above) where weekly consumption increases significantly

Paton MW, Kalemtzaki E, Stoewen D, Hameedunisha T, Yang H, Donlin J, Endenburg N (2024) WSAVA professional wellness guidelines
