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However, another GLS inhibitor, the small molecule 968, can suppress GLS2 effectively and inhibit cell growth and proliferation in BPTES-resistant breast cancer [74]

These findings align with earlier investigations in high glucoseinduced C57BL/6 mice treated with PB2, indicating that PCs regulate lipid metabolism in diabetes by targeting endoplasmic reticulum sensors such as PERK, IRE1, and ATF6 (Zhaoxia et al., 2014)

In: Carruthers SG, Hoffman BB, Melmon KL, et al., editors

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