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doi: 10.1016/j.cub.2018.05.094 129 ChenLLiuSTaoY

Changes in the tumor microenvironment Extracellular matrix remodeling The effects of the extracellular matrix (ECM) on cells are primarily mediated by integrins, a family of cell surface receptors that attach cells to the matrix and trigger signal transduction [117]

Targeting these crosstalk pathways in breast cancer remains an active area of clinical investigation

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10.1016/j.ejps.2022.106324 279 VermaasJ
