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Oxidative damage further exacerbates mitochondrial dysfunction, increasing outer membrane permeability (MOMP) and disrupting bioenergetic homeostasis [47, 48]

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Nature 489, 318321

The time it takes to see results with PDA as it depends on the severity of the injury

Fukumoto M, Kondo K, Uni K, Ishiguro T, Hayashi M, Ueda S, et al

Frankel AE, Konopleva M, Hogge D, Rizzieri D, Brooks C, Cirrito T, Kornblau SM, Borthakur G , Bivins C, Garcia-Manero G, Ravandi F, Kadia TM, Andreeff M, Cortes JE, Hoberman K, Szarek M, Bergstein I, Kantarjian HM, Rowinsky EK