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Coenzyme Q10 ameliorates inflammation, oxidative stress, and testicular histopathology in rats exposed to heat stress
Disulfiram (DS), a clinically used anti-alcoholism drug, strongly inhibits constitutive and 5-FU-induced NF-kappaB activity in a dose-dependent manner

Some GTK activity is also found in rat kidney and liver mitochondria, but the role of mitochondrial GTK as a cysteine S -conjugate -lyase is uncertain
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Direct antioxidant administration, such as vitamins C and E, has also shown limited efficacy due to poor bioavailability and inadequate targeting of mitochondrial ROS production 17

Nerve impulses promote the release of NO from endothelial cells
