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You can always increase doses based on response

On the contrary, CUR/miR155@DssD-Hb NPs and CUR@DssD-Hb NPs increasingly facilitated CRT expression of B16F10 tumor cells, suggesting substantial tumor cell death with immunogenic properties

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Signal 12, 781786

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In addition, intranasal infection of hACE2 transgenic mice with SARS-CoV-1 caused severe CNS infections that spread from the olfactory bulb to the basal ganglia and midbrain within approximately four days (69)
