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It has been reported that berberine is widely used in many traditional medical systems, including Ayurvedic, Iranian, and Chinese medicine (Kunwar et al., 2006

pmid:26597770CrossRefPubMedGoogle Scholar Herrmann W, Obeid R

This aligns with the position of major medical organizations, including the American Cancer Society and National Cancer Institute, which do not recognize coffee enemas as having any proven therapeutic value

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Each infusion is administered by a licensed medical professional, with treatment options determined based on patient needs and clinical appropriateness