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Nutrition: Favor a balanced, nutrient-dense diet rich in antioxidants and anti-inflammatory foods

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Iron-induced oxidative stress in human diseases

Dysfunctional mitophagy and impaired mitochondrial quality control Mitochondria maintain their functional integrity through a coordinated quality control network, which includes mitochondrial fission and fusion, proteolytic degradation of oxidized/damaged proteins, and the removal and/or recycle of dysfunctional mitochondria via mitophagy [55, 56]

doi: 10.3390/ijms23020678, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Ben-Shlomo Y., Darweesh S., Llibre-Guerra J., Marras C., San Luciano M., Tanner C

KW-6356 is a second-generation A2A antagonist which has shown positive results with regard to motor progression in early-stage PD, as assessed by changes in the MDS-UPDRS motor score from baseline until the end of follow-up, both in combination with levodopa (NCT03703570) and as monotherapy (NCT02939391, Table 2) (Chen et al
