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Figure 2 shows the proposed molecular mechanism of action

A constant airflow of 1 or 2 NL min 1 was maintained from the bottom through a sparger, corresponding to an aeration of 0.5 and 1 vvm, respectively

Pregnancy and breastfeeding represent absolute contraindications requiring immediate discontinuation regardless of dose
With regard to pregnancy, breastfeeding or any serious condition a healthcare professional can advise

doi: 10.1002/jmv.24810 [DOI] [PMC free article] [PubMed] [Google Scholar] 131

hence, it can be recommended as adjuvant therapy alongside MTX to counteract its cytotoxic adverse effects
