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Clinical translation requires addressing challenges including cell-type specificity, development of disease-specific ferroptosis biomarkers, optimization of combination regimens, and careful safety assessment to avoid unintended effects such as myelosuppression or hepatorenal toxicity

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See TABLE 3 for a list of medications that can cause gynecomastia

The metabolic regulatory roles of BAs in lipid and glucose metabolism, as well as insulin sensitivity, are associated with the expression of the FXR and TGR5 receptors (Zhang et al., 2006)

doi: 10.1016/J.SAJB.2016.03.011 190 TalaatN

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