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Alternatively activated macrophages (M2 macrophages), on the other hand, are characterized by upregulation of markers such as CD206, arginase-1, IL-10, and TGF- [20,21] ( Figure 1 )

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2.2 Salinity, GSH and BSO treatment Healthy thalli were cultured in mediums of natural seawater diluted with 0% (v:v), 50%, and 100% sterilized freshwater, i.e., salinity of ~ 30 psu, 15 psu, 0 psu, respectively, at 14C, 40 mol photons m 2 s 1 , pH 8.0, 12 h:12 h L: D