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Hyperpigmentation occurs when the skin produces more melanin, the pigment that gives skin its colour, explained Medical News Today

Metastasis 25 , 377388 (2008)

Tyrosinase (TYR), Tyrosinase-related proteins-1 (TRP-1) and TRP-2 (also known as dopachrome tautomerase) are the three important enzymes involved in melanogenesis

Lactobacillus treatment attenuated intestinal oxidative stress changes by lowering intestinal MDA and boosting GSH content, SOD3 activity, Nrf2, and OH-1

Key Points: Brightening + Well-Ageing

Whether it is eating or smoking a joint, this behavior is used in a healthy way, like eating when hungry or relaxing with friends