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Epigenetic modifications in drug resistance Alternative splicing Splicing events after the post transcription process matures the mRNA to become respective functional protein

Vitamin B12 Deficiency Vitamin B12 is an essential nutrient that supports healthy nervous system function, so its not surprising that a vitamin B12 deficiency may contribute to paresthesia a tingling or numb sensation that commonly affects the arms, hands, legs, or feet

Even a 0.01% difference in genetic matter can be substantial to making a big difference, depending, on where such differences lie in the genome, and what effects such difference have in the complex interactions of molecular pathways

(1) Liska D, Quinn S, Lukaczer D, Jones DS, Lerman RH

Safety concerns, including hypokalemia, sedation, and teratogenicity, also restrict use