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Description
Br J Cancer 2011

The neurological syndromes associated with glutamic acid decarboxylase antibodies

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Approximately three quarters of these patients have other clear signs and symptoms of central nervous system involvement, occasionally with onset and progression in the teenage years (71

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A high extracellular glutamate concentration was one of the first xCT inhibitors described but a few years later, erastin (standing for eradicator of RAS and small T antigen-expressing cells) was identified by Stockwell's group in RAS-mutated cancer cell lines as inhibitor of xCT transport (42)
